Studies show that harmful ingredients such as triphenyl phosphate (TPHP) enter the body through nail polish application. TPHP is associated with endocrine disruption. Exposure to VOCs like acetone, methyl methacrylate (MMA), and toluene is associated with headaches, lightheadedness, and irritation to the nose, eyes, throat, and skin. Benzephenone-1 is associated with endocrine disruption and skin toxicity, and may accelerate growth of breast cancer cells and promote cancer metastasis. Sienna Byron Bay nail polishes are the cleanest option, free of harmful ingredients including benzephenone-1.